High Anti–Phenolic Glycolipid-I IgM Titers and Hidden Leprosy Cases, Amazon Region
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چکیده
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منابع مشابه
Schoolchildren Survey and Community Survey for The Determination of Seroprevalence Against IgM Anti Phenolic Glycolipid - I Antibody in Leprosy Endemic Areas , South Sulawesi , Indonesia
This study rePorts on the usefulness of IgM anti phenolic glycolipid-l (PGL-I) antibody detection using Mycobacterium leprae particle agglutination (MLPA) test in a schoolchildren survey comparedwith a community surtey in leprosy endemic areas, Indonesia. Two villages with total registered persons 1729 and 3077 respectively were chosen to determine the seroprevalence ofeach village. Among 510 a...
متن کاملPrevalence of IgM antibodies to phenolic glycolipid I among household contacts and controls in Korea and the Philippines.
Phenolic glycolipid I (PGL-I) is a Mycobacterium leprae-specific antigen and the antibodies to the antigen may suggest an M. leprae infection. To compare the M. leprae transmission among the populations, we compared the prevalence of anti-PGL-I IgM antibodies among household contacts and controls between Korea and the Philippines. In Korea (prevalence of leprosy--0.04: 1000), the prevalence of ...
متن کاملDetermination of the Salivary Anti-Phenolic Glycolipid-1 Antibody in Leprosy Patients as a Tool to Monitoring Multidrugtherapy
Problem statement: The upper airways has a great importance as a route of M. leprae infection and because of the possibility of identifying relevant tools by systematic patient evaluation, the detection of leprosy patients by means of salivary markers becomes important. The aim of this study was to analyze anti-phenolic glycolipid 1 (anti-PGL-1) salivary and serum titers as parameters for corre...
متن کاملHigh rates of undiagnosed leprosy and subclinical infection amongst school children in the Amazon Region.
Leprosy in children is correlated with community-level factors, including the recent presence of disease and active foci of transmission in the community. We performed clinical and serological examinations of 1,592 randomly selected school children (SC) in a cross-sectional study of eight hyperendemic municipalities in the Brazilian Amazon Region. Sixty-three (4%) SC, with a mean age of 13.3 ye...
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This study reports the evaluation of the presence of IgM antibody to Phenolic Glycolipid-I (PGL-I) of M. leprae andT cell subsets (CD4 and CD|) count to determine the high risk to contract leprosy among individuals through a total PoPulntion survey in an area where leprosy is endemic, in IndonesiaAmong the 2349 individuals of the total population of 3074 people, the seropositive rates in genera...
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